Lt.Col. Mesud Cerit, PhD (Physical Education and Training Branch of J 3 Turkish General Staff) RELATIONSHIP BETWEEN ACE GENOTYPE AND SHORT DURATION AEROBİC PERFORMANCE DEVELOPMENT

RELATIONSHIP BETWEEN ACE GENOTYPE AND SHORT DURATION AEROBİC PERFORMANCE DEVELOPMENT

MESUT CERIT1, MUZAFFER COLAKOGLU2, SIRRI CAM3, MURAT ERDOGAN4, AFIG BERDELI5

1 Ege University, Institute of Health Sciences, Sport Sciences Division, Izmir, Turkey
2 Ege University, School of Physical Education and Health, Dept. of Coaching Education, Izmir, Turkey
3 Celal Bayar University, Faculty of Medicine, Dept. of Medical Biology and Genetics, Manisa, Turkey
4 Gazi University, Institute of Health Sciences, Physical Education and Sports Division, Izmir, Turkey
5 Ege University, Faculty of Medicine, Dept. of Pediatrics, Molecular Diagnostics Laboratory, Izmir, Turkey

ABSTRACT

We have previously demonstrated that, ACE D allele may be related with a better performance in short duration aerobic endurance in a homogeneous cohort with similar training backgrounds. We aimed to study the variation in the short - duration aerobic performance development amongst ACE genotypes in response to identical training programs in homogeneous populations.
The study group consisted of 186 male Caucasian non-elite Turkish army recruits. All subject had undergone an identical training program with double training session per day and six days a week for six months. Performances for middle distance runs (2,400 m) were evaluated on an athletics track before and after the training period. ACE gene polymorphisms were studied by PCR analysis.
The distribution of genotypes in the whole group was 16.7% II, n=31; 46.2% ID, n=86; 37.1% DD, n=69. Subjects with ACE DD genotype had significantly higher enhancement than the ID (p<0.01) and II (p<0.05) genotype groups. 2,400 m performance enhancement ratios showed a linear trend as ACE DD > ACE ID > ACE II (P value for Pearson χ2 = 0.461 and P value for linear by linear association = 0.001).
ACE DD genotype seems to have an advantage in development in short-duration aerobic performance. This data in unison with the data that we have obtained from homogenous cohorts previously is considered as an existence of threshold for initiation of ACE I allele effectiveness in endurance performance. This threshold may be anywhere between 10 and 30 minutes with lasting maximal exercises.
Key words: Genetics, Endurance- Insertion/deletion -Training-ACE